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Cilia are slender, microscopic, hair-like structures or organelles that extend from the ... When the cilia are defective, there is no signal and too much cell division, ...
29 Oct 2014 ... In the airways, cilia function in concert with airway mucus to mediate the critical ... maintenance of human airway cilia is not well understood, and likely involves a ... Matsui H, Grubb BR, Tarran R, Randell SH, Gatzy JT, et al. ... genes associated with primary ciliary dyskinesia and genes down-regulated by ...
Keywords: cilia, mucine, mucociliary clearance, mucus, pharmacokinetics ... be carried out in such a way that it does not affect normal functions of the nose. ... and clear them down to the nasopharynx, then otopharynx and hypopharynx from ... 37) Tarran R, Grubb BR, Parsons D, Picher M, Hirsh AJ, Davis CW, Boucher RC.
Primary cilia disassembly down-regulates mechanosensitive hedgehog ... Pathway activation requires a functioning primary cilium and is not observed in ... Besschetnova T.Y., Kolpakova-Hart E., Guan Y., Zhou J., Olsen B.R., Shah J.V. ...