15 May 2020 ... Therefore, overabundance of STAU1 might not be necessary to mediate its ... Vessey JP, Macchi P, Stein JM, Mikl M, Hawker KN, Vogelsang P, et al. ... Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 ... Cell Death Differ (2020). https://doi.org/10.1038/s41418-020-0553-9.
29 Jun 2020 ... [email protected]; Author profile · Search articles by ORCID ... Department of Surgery, Kaohsiung Medical University Hospital, No. ... which breast cancer cells resist apoptosis is still not fully elucidated. ... Grant ID: kmtth-103-008 ... Twitter · Blog · Tech blog · Developer forum. Let us know how we are ...
The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic ... ER through retrotranslocation, where it is broken down by the ubiquitin-proteasome pathway as part of the ERAD system. ... However, the point at which the 'apoptotic switch' is activated has not yet been determined, but it is a ...
12 Dec 2015 ... A recent study has shown that saturated fatty acid palmitate induced ... To determine the activation of unfolded protein response (UPR) signaling, cell lysates were ... Treatment of isolated primary meniscus cells with palmitate but not oleate ... Knocking down the activity of Ire1α inhibited palmitate- induced ...
are first received by the cell, they not only recruit and ac- ... This article is available online at http://www.jlr.org ... down-stream signaling (13, 14). Not all PH ...
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caused comparable killing of Bax- or Bak-expressing MEFs (de- scribed in A), far more ... cell death does not ensue on down-regulation of Mcl-1 by either RNAi ...
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... from Ensembl if not indicated otherwise. Gene name, MED24 (HGNC Symbol) ... at protein level). neXtProt, NX_O75448. Antibodypedia, MED24 antibodies ...
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions ...
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RTL9 (KIAA1318, Mar9, Mart9, RGAG1, SIRH10) protein expression summary. ... from Ensembl if not indicated otherwise. Gene name, RTL9 (HGNC Symbol).
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tion is well characterized, little is known about its down- ... stress response and in vivo glucose homeostasis. unfolded protein response ... Homozygous eIF2 Ser51Ala MEFs Do Not Attenuate Translation and Die after ER Stress. (A) ER stress ... Fawcett, T.W., Martindale, J.L., Guyton, K.Z., Hai, T., and Holbrook,. N.J. (1999).
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