14 Nov 2019 ... The fate of an intron to be, or not to be, retained in the mature transcript ... of genes with neuron-specific functions and down-regulation of genes ...
Moreover, retained introns that are predicted not to introduce an NMD-eliciting ... to down-regulate transcripts from genes, the expression of which is either not ...
8 Apr 2017 ... However, the “non-productive” label should not be taken to imply lack ... Intron retention is most often associated with down-regulation of gene ...
11 Apr 2018 ... IntEREst is an R package for Intron retention and exon-exon junction ... application of IntEREst is not limited to the comparison of these intron types. ... This results in a more symmetric distribution of up/down regulated intron retention signals (Fig ... Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, ...
16 Nov 2017 ... Intron-retaining genes have significantly longer 3′ UTR sequences, with a ... We argue therefore in zebrafish that IR is not as important ... Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, Alipanahi ... is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6.
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While introns do not encode protein products, they are integral to gene expression regulation. Some introns themselves encode functional RNAs through further ...
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This policy is effective for the website “http://paradigm-shift.co/” on the Internet, and other websites and ... e-mail: [email protected] ... Paradigm Shift will not share any personal data acquired through the website with a Third Party, ...
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